Hyaluronic acid has long been a darling of both dermatologists and skincare enthusiasts for its remarkable ability to hydrate, plump, and revitalize the skin. This powerhouse ingredient is renowned for its compatibility with other skincare components and its gentle effectiveness that suits all skin types. Over the years, hyaluronic acid has become a ubiquitous component in a myriad of skincare products, ranging from cleansers to moisturizers. However, it shines brightest in serum form, where its benefits are delivered intensely and effectively.
Today, hyaluronic acid serums are not just about simple hydration; they are crafted with precision to address a variety of skincare concerns, such as acne and signs of aging, making them versatile additions to any skincare routine. To simplify your search through the vast options available at retailers like Sephora and Ulta, we’ve consulted with dermatologists and beauty experts to bring you their top picks for hyaluronic acid serums that promise dewy, glowing skin.

Top Dermatologist-Approved Hyaluronic Acid Serums
1. La Roche-Posay Hyalu-B5 Serum
- Size: 1.01 oz.
- Key Ingredients: Hyaluronic acid, madecassoside, glycerin, vitamin B5
- Skin Types: All
What Stands Out: La Roche-Posay’s Hyalu-B5 Serum has garnered accolades for being particularly effective for dry skin. It features a sophisticated formula with two types of hyaluronic acid for multi-level hydration: vitamin B5 to lock in moisture and centella asiatica to soothe irritation. Dr. Margarita Lolis praises its immediate hydrating effects, which leave the skin feeling refreshed and plump. Its accessibility and affordability at drugstores make it a standout choice.
Improvement Points: The price point is slightly higher for a drugstore product, but the benefits justify the investment.
2. Avène Hydrance Boost Serum
- Size: 1 oz.
- Key Ingredients: Hyaluronic acid, vitamin B3, Avène thermal spring water
- Skin Types: Dry, dehydrated, sensitive
What Stands Out: This serum is a hydration powerhouse, thanks to its blend of hyaluronic acid, niacinamide, and Avène’s signature thermal spring water. Dr. Lolis highlights the spring water’s soothing properties, which alleviate skin tightness and restore balance. Its gel-water texture is refreshing and perfect for deep, lasting hydration.
Improvement Points: Some users may find the texture slightly sticky, although this does not detract significantly from its overall effectiveness.

3. Glossier Super Bounce Serum
- Size: 1 oz.
- Key Ingredients: Hyaluronic acid, vitamin B5, glycerin
- Skin Types: Normal, combination, oily, acne-prone
What Stands Out: Ideal for acne-prone skin, this lightweight serum provides intense hydration without exacerbating acne or causing irritation. Its formulation is perfect for strengthening the skin barrier and improving texture, contributing to a decrease in breakouts for many users.
Improvement Points: While it’s excellent for oily and acne-prone skin, it may not provide sufficient hydration for those with very dry skin.
4. The Ordinary Lactic Acid 10% + HA 2% Exfoliating Serum
- Size: 1 oz.
- Key Ingredients: Lactic acid, hyaluronic acid, Tasmanian pepperberry
- Skin Types: Normal, oily, combination, acne-prone
What Stands Out: This unique serum combines hydration with exfoliation. Lactic acid helps to reduce surface oils and enhance skin texture, while hyaluronic acid ensures deep hydration. The inclusion of Tasmanian pepper berry mitigates any potential irritation from the exfoliation, making it a perfect choice for oily and combination skin types looking to balance moisture and maintain a healthy glow.
Improvement Points: It may not be suitable for dry or very sensitive skin due to its exfoliating properties.
These hyaluronic acid serums come highly recommended by dermatologists for their effective formulations and ability to cater to various skin needs. Whether you’re looking to soothe dry skin, enhance your glow, or balance hydration in oily skin, there’s a serum here that can help achieve your skincare goals.